Effect of oil loading on microspheres produced by spray drying

被引:120
作者
Tan, LH [1 ]
Chan, LW [1 ]
Heng, PWS [1 ]
机构
[1] Natl Univ Singapore, Fac Sci, Dept Pharm, Singapore 117543, Singapore
关键词
spray drying; fish oil; oil loading;
D O I
10.1080/02652040500100329
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Oil-loaded microspheres were produced by spray drying emulsions consisting of fish oil and modified starch suspensions with different oil loadings. The emulsion stability was assessed by oil droplet size analysis. Microspheres were characterized in terms of size, morphology, yield and microencapsulation efficiency. It was found that an increase in oil loading resulted in emulsions containing larger oil droplets. This corresponded with larger mean microsphere diameters and rounder microspheres. However, high oil loadings produced lower yields and affected microencapsulation efficiencies.
引用
收藏
页码:253 / 259
页数:7
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