Prophylaxis failure is associated with a specific Pneumocystis carinii genotype

被引:21
作者
Hauser, PM [1 ]
Sudre, P [1 ]
Nahimana, A [1 ]
Francioli, P [1 ]
机构
[1] CHU Vaudois, Div Autonome Med Prevent Hosp, CH-1011 Lausanne, Switzerland
关键词
D O I
10.1086/322659
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
To investigate the possible association between Pneumocystis carinii types and various clinical and demographic parameters, we used molecular typing to analyze 93 bronchoalveolar lavage specimens from patients with P. carinii pneumonia (PCP). Multivariate regression analysis revealed an association between being infected with a specific P. carinii genotype and receiving anti-PCP prophylaxis (odds ratio, 4.4; 95% confidence interval, 1.0-18.6; P=.05), although no association with a specific drug was detected.
引用
收藏
页码:1080 / 1082
页数:3
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