Influence of amino acid substitutions in the leader peptide on maturation and secretion of mesentericin Y105 by Leuconostoc mesenteroides

被引：24

作者：

Aucher, W ^{[1
]}

Lacombe, C ^{[1
]}

Héquet, A ^{[1
]}

Frère, J ^{[1
]}

Berjeaud, JM ^{[1
]}

机构：

[1] Univ Poitiers, CNRS, Inst Biol Mol & Ingn Genet, Equipe Microbiol Fondamentale & Appl,UMR 6008, Poitiers, France

来源：

JOURNAL OF BACTERIOLOGY | 2005年 / 187卷 / 06期

关键词：

D O I：

10.1128/JB.187.6.2218-2223.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

By site-specific mutagenesis, the hydrophobic conserved amino acids and the C-terminal GG doublet of the leader peptide of pre-mesentericin Y105 were demonstrated to be critical for optimal secretion of mesentericin Y105, as well as for the maturation of the pre-bacteriocin by the protease portion of the ABC transporter MesD.

引用

页码：2218 / 2223

页数：6

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