Multiple sequence alignments

被引：66

作者：

Wallace, IM ^{[1
]}

Blackshields, G ^{[1
]}

Higgins, DG ^{[1
]}

机构：

[1] Univ Coll Dublin, Conway Inst Biomol & Biomed Res, Dublin 2, Ireland

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 2005年 / 15卷 / 03期

关键词：

D O I：

10.1016/j.sbi.2005.04.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Multiple sequence alignments are very widely used in all areas of DNA and protein sequence analysis. The main methods that are still in use are based on 'progressive alignment' and date from the mid to late 1980s. Recently, some dramatic improvements have been made to the methodology with respect either to speed and capacity to deal with large numbers of sequences or to accuracy. There have also been some practical advances concerning how to combine three-dimensional structural information with primary sequences to give more accurate alignments, when structures are available.

引用

页码：261 / 266

页数：6

共 46 条

[1] Combining multiple structure and sequence alignments to improve sequence detection and alignment: Application to the SH2 domains of Janus kinases [J].

Al-Lazikani, B ;

Sheinerman, FB ;

Honig, B .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (26) :14796-14801

[2]

[Anonymous], LECT NOTES COMPUTER

[3]

Bailey T L, 1994, Proc Int Conf Intell Syst Mol Biol, V2, P28

[4] A STRATEGY FOR THE RAPID MULTIPLE ALIGNMENT OF PROTEIN SEQUENCES - CONFIDENCE LEVELS FROM TERTIARY STRUCTURE COMPARISONS [J].

BARTON, GJ ;

STERNBERG, MJE .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 198 (02) :327-337

[5] MAVID: Constrained ancestral alignment of multiple sequences [J].

Bray, N ;

Pachter, L .

GENOME RESEARCH, 2004, 14 (04) :693-699

[6] Fast and sensitive multiple alignment of large genomic sequences -: art. no. 66 [J].

Brudno, M ;

Chapman, M ;

Göttgens, B ;

Batzoglou, S ;

Morgenstern, B .

BMC BIOINFORMATICS, 2003, 4 (1)

[7] LAGAN and Multi-LAGAN: Efficient tools for large-scale multiple alignment of genomic DNA [J].

Brudno, M ;

Do, CB ;

Cooper, GM ;

Kim, MF ;

Davydov, E ;

Green, ED ;

Sidow, A ;

Batzoglou, S .

GENOME RESEARCH, 2003, 13 (04) :721-731

[8] MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING [J].

CORPET, F .

NUCLEIC ACIDS RESEARCH, 1988, 16 (22) :10881-10890

[9] ProbCons: Probabilistic consistency-based multiple sequence alignment [J].

Do, CB ;

Mahabhashyam, MSP ;

Brudno, M ;

Batzoglou, S .

GENOME RESEARCH, 2005, 15 (02) :330-340

[10] MUSCLE: a multiple sequence alignment method with reduced time and space complexity [J].

Edgar, RC .

BMC BIOINFORMATICS, 2004, 5 (1) :1-19

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