Bone marrow myeloid cells in regulation of multiple myeloma progression

被引：11

作者：

Herlihy, Sarah E. ^{[1
]}

Lin, Cindy ^{[1
]}

Nefedova, Yulia ^{[1
]}

机构：

[1] Wistar Inst Anat & Biol, Tumor Microenvironm & Metastasis Program, 3601 Spruce St,Room 376, Philadelphia, PA 19104 USA

来源：

CANCER IMMUNOLOGY IMMUNOTHERAPY | 2017年 / 66卷 / 08期

关键词：

Multiple myeloma; Cancer; Neutrophils; Myeloid-derived suppressor cells; Regulatory myeloid suppressor cells; Chemoresistance; NEUTROPHIL EXTRACELLULAR TRAPS; PLASMACYTOID DENDRITIC CELLS; TUMOR-ASSOCIATED MACROPHAGES; MEDIATED DRUG-RESISTANCE; SUPPRESSOR-CELLS; RECEPTOR ACTIVATOR; SURVIVAL; CANCER; EXPRESSION; PROMOTE;

D O I：

10.1007/s00262-017-1992-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Survival, growth, and response to chemotherapy of cancer cells depends strongly on the interaction of cancer cells with the tumor microenvironment. In multiple myeloma, a cancer of plasma cells that localizes preferentially in the bone marrow, the microenvironment is highly enriched with myeloid cells. The majority of myeloid cells are represented by mature and immature neutrophils. The contribution of the different myeloid cell populations to tumor progression and chemoresistance in multiple myeloma is discussed.

引用

页码：1007 / 1014

页数：8

共 52 条

[1]

Osteoclasts enhance myeloma cell growth and survival via cell-cell contact: a vicious cycle between bone destruction and myeloma expansion [J].

Abe, M ;

Hiura, K ;

Wilde, J ;

Shioyasono, A ;

Moriyama, K ;

Hashimoto, T ;

Kido, S ;

Oshima, T ;

Shibata, H ;

Ozaki, S ;

Inoue, D ;

Matsumoto, T .

BLOOD, 2004, 104 (08) :2484-2491

[2]

[Anonymous], 2020, CANC FACTS FIGURES 2

[3]

CD28-mediated regulation of multiple myeloma cell proliferation and survival [J].

Bahlis, Nizar J. ;

King, Anne M. ;

Kolonias, Despina ;

Carlson, Louise M. ;

Liu, Hong Yu ;

Hussein, Mohamad A. ;

Terebelo, Howard R. ;

Byrne, Gerald E., Jr. ;

Levine, Bruce L. ;

Boise, Lawrence H. ;

Lee, Kelvin P. .

BLOOD, 2007, 109 (11) :5002-5010

[4]

Bain BJ., 2001, BONE MARROW PATHOLOG, V3rd

[5]

A proposed role for neutrophil extracellular traps in cancer immunoediting [J].

Berger-Achituv, Sivan ;

Brinkmann, Volker ;

Abu Abed, Ulrike ;

Kuehn, Lars I. ;

Ben-Ezra, Jonathan ;

Elhasid, Ronit ;

Zychlinsky, Arturo .

FRONTIERS IN IMMUNOLOGY, 2013, 4

[6]

Bortezomib-induced pro-inflammatory macrophages as a potential factor limiting anti-tumour efficacy [J].

Beyar-Katz, Ofrat ;

Magidey, Ksenia ;

Ben-Tsedek, Neta ;

Alishekevitz, Dror ;

Timaner, Michael ;

Miller, Valeria ;

Lindzen, Moshit ;

Yarden, Yosef ;

Avivi, Irit ;

Shaked, Yuval .

JOURNAL OF PATHOLOGY, 2016, 239 (03) :262-273

[7]

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma [J].

Binsfeld, Marilene ;

Muller, Josephine ;

Lamour, Virginie ;

De Veirman, Kim ;

De Raeve, Hendrik ;

Bellahcene, Akeila ;

Van Valckenborgh, Els ;

Baron, Frederic ;

Beguin, Yves ;

Caers, Jo ;

Heusschen, Roy .

ONCOTARGET, 2016, 7 (25) :37931-37943

[8]

Impaired functionality and phenotypic profile of dendritic cells from patients with multiple myeloma [J].

Brimnes, MK ;

Svane, IM ;

Johnsen, HE .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2006, 144 (01) :76-84

[9]

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards [J].

Bronte, Vincenzo ;

Brandau, Sven ;

Chen, Shu-Hsia ;

Colombo, Mario P. ;

Frey, Alan B. ;

Greten, Tim F. ;

Mandruzzato, Susanna ;

Murray, Peter J. ;

Ochoa, Augusto ;

Ostrand-Rosenberg, Suzanne ;

Rodriguez, Paulo C. ;

Sica, Antonio ;

Umansky, Viktor ;

Vonderheide, Robert H. ;

Gabrilovich, Dmitry I. .

NATURE COMMUNICATIONS, 2016, 7

[10]

Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target [J].

Chauhan, Dharminder ;

Singh, Ajita V. ;

Brahmandam, Mohan ;

Carrasco, Ruben ;

Bandi, Madhavi ;

Hideshima, Teru ;

Bianchi, Giada ;

Podar, Klaus ;

Tai, Yu-Tzu ;

Mitsiades, Constantine ;

Raje, Noopur ;

Jaye, David L. ;

Kumar, Shaji K. ;

Richardson, Paul ;

Munshi, Nikhil ;

Anderson, Kenneth C. .

CANCER CELL, 2009, 16 (04) :309-323

← 1 2 3 4 5 6 →