Design of excitatory amino acid receptor agonists, partial agonists and antagonists: Ibotenic acid as a key lead structure

被引：54

作者：

KrogsgaardLarsen, P ^{[1
]}

Ebert, B ^{[1
]}

Lund, TM ^{[1
]}

Brauner-Osborne, H ^{[1
]}

Slok, FA ^{[1
]}

Johansen, TN ^{[1
]}

Brehm, L ^{[1
]}

Madsen, U ^{[1
]}

机构：

[1] ROYAL DANISH SCH PHARM, PHARMACOBIOTEC RES CTR, DEPT BIOL, DK-2100 COPENHAGEN, DENMARK

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1996年 / 31卷 / 7-8期

关键词：

excitatory amino acid (EAA) receptor; ionotropic EAA receptor; metabotropic EAA receptor; AMPA agonist; AMPA partial agonist; AMPA antagonist; AMPA receptor modulator; kainic acid agonist; kainic acid antagonist; NMDA agonist; NMDA antagonist; glycine agonist; glycine partial agonist; glycine antagonist; metabotropic EAA agonist; metabotropic EAA antagonist; receptor autoradiography; functional partial agonism; EAA and neurodegeneration; EAA and schizophrenia; EAA and Alzheimer's disease;

D O I：

10.1016/0223-5234(96)89549-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：515 / 537

页数：23

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