The effect of cholecystokinin in controlling appetite and food intake in humans

被引:78
作者
Degen, L
Matzinger, D
Drewe, J
Beglinger, C [1 ]
机构
[1] Univ Basel Hosp, Div Gastroenterol, CH-4031 Basel, Switzerland
[2] Univ Basel Hosp, Div Pharmacol, CH-4031 Basel, Switzerland
关键词
D O I
10.1016/S0196-9781(01)00450-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The present review of the satiating effect of cholecystokinin in humans has revealed that cholecystokinin is a physiological satiety factor in humans. The results demonstrate the efficacy of the satiating actions of exogenous and endogenous CCK in humans. The therapeutic potential of CCK analogues cannot be estimated until further studies are performed that demonstrate the efficacy of CCK analogues for decreasing body weight, and the safety of CCK when administered repetitively for prolonged periods. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:1265 / 1269
页数:5
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