A combined neutron scattering and simulation study on bioprotectant systems

被引：52

作者：

Affouard, F

Bordat, P

Descamps, M

Lerbret, A

Magazù, S

Migliardo, F ^{[1
]}

Ramirez-Cuesta, AJ

Telling, MFT

机构：

[1] Univ Lille 1, Lab Dynam & Struct Mat Mol, UMR 8024, F-59655 Villeneuve Dascq, France

[2] Univ Messina, Dipartimento Fis, I-98166 Messina, Italy

[3] Univ Messina, INFM, I-98166 Messina, Italy

[4] Rutherford Appleton Lab, ISIS Facil, Didcot OX11 0QX, Oxon, England

来源：

CHEMICAL PHYSICS | 2005年 / 317卷 / 2-3期

关键词：

disaccharides; water mixtures; dynamical properties; bioprotective effects; neutron scattering;

D O I：

10.1016/j.chemphys.2005.05.033

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The present work shows quasi elastic neutron scattering, neutron spin echo and inelastic neutron scattering results on a class of bioprotectant systems, such as homologous disaccharides (i.e., trehalose and sucrose)/water solutions, as a function of temperature. The whole set of findings indicates a noticeable "kosmotrope" character of the disaccharides, and in particular of trehalose, which is able to strongly modify both the structural and dynamical properties of water. This superior capability of trehalose can be linked to its higher bioprotective effectiveness in respect with the other disaccharides. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：258 / 266

页数：9

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