Unnatural natural products from the transannular cyclization of lathyrane diterpenes

被引：50

作者：

Appendino, G

Tron, GC

Jarevång, T

Sterner, O

机构：

[1] Univ Piemonte Orientale, DiSCAFF, I-28100 Novara, Italy

[2] Univ Lund, Dept Organ Chem, S-22100 Lund, Sweden

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 11期

关键词：

D O I：

10.1021/ol0155541

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The potential of macrocyclic diterpenoids to afford natural product like polycyclic compounds was demonstrated by the conversion of two lathyrane Euphorbia factors into a series of densely functionalized diterpenoids of unnatural skeletal type. Apparently, Nature is far from having fully exploited the built-in reactivity of these compounds to generate chemical diversity.

引用

页码：1609 / 1612

页数：4

共 24 条

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