学术探索
学术期刊
新闻热点
数据分析
智能评审

Human immunodeficiency virus type 1 tropism for T-lymphoid cell lines: Role of the V3 loop and C4 envelope determinants

被引：77
作者：
Carrillo, A
Ratner, L
机构：
[1] WASHINGTON UNIV,SCH MED,DEPT MED,ST LOUIS,MO 63110
[2] WASHINGTON UNIV,SCH MED,DEPT PATHOL,ST LOUIS,MO 63110
[3] WASHINGTON UNIV,SCH MED,DEPT MOLEC MICROBIOL,ST LOUIS,MO 63110
来源：
JOURNAL OF VIROLOGY | 1996年 / 70卷 / 02期
关键词：
D O I：
10.1128/JVI.70.2.1301-1309.1996
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A functional analysis of chimeric proviral clones generated from the T-cell line-tropic isolate HXB2 and the non-T-cell line-tropic isolate YU-2 identified the minimal determinant for infection of T-lymphoid cell lines to include two interacting domains: the V3 loop and a small region of the C4 domain.
引用
收藏
页码：1301 / 1309
页数：9
相关论文
共 86 条
  • [1] PRODUCTION OF ACQUIRED IMMUNODEFICIENCY SYNDROME-ASSOCIATED RETROVIRUS IN HUMAN AND NONHUMAN CELLS TRANSFECTED WITH AN INFECTIOUS MOLECULAR CLONE
    ADACHI, A
    GENDELMAN, HE
    KOENIG, S
    FOLKS, T
    WILLEY, R
    RABSON, A
    MARTIN, MA
    [J]. JOURNAL OF VIROLOGY, 1986, 59 (02) : 284 - 291
  • [2] BOTH THE V2 AND V3 REGIONS OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 SURFACE GLYCOPROTEIN FUNCTIONALLY INTERACT WITH OTHER ENVELOPE REGIONS IN SYNCYTIUM FORMATION
    ANDEWEG, AC
    LEEFLANG, P
    OSTERHAUS, ADME
    BOSCH, ML
    [J]. JOURNAL OF VIROLOGY, 1993, 67 (06) : 3232 - 3239
  • [3] TRANS-ACTIVATOR GENE OF HUMAN T-LYMPHOTROPIC VIRUS TYPE-III (HTLV-III)
    ARYA, SK
    GUO, C
    JOSEPHS, SF
    WONGSTAAL, F
    [J]. SCIENCE, 1985, 229 (4708) : 69 - 73
  • [4] ASJO B, 1986, LANCET, V2, P660
  • [5] HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ENVELOPE GLYCOPROTEIN MOLECULES CONTAINING MEMBRANE FUSION-IMPAIRING MUTATIONS IN THE V3-REGION EFFICIENTLY UNDERGO SOLUBLE CD4-STIMULATED GP120 RELEASE
    BERGER, EA
    SISLER, JR
    EARL, PL
    [J]. JOURNAL OF VIROLOGY, 1992, 66 (10) : 6208 - 6212
  • [6] THE BLOCK TO HIV-1 ENVELOPE GLYCOPROTEIN-MEDIATED MEMBRANE-FUSION IN ANIMAL-CELLS EXPRESSING HUMAN CD4 CAN BE OVERCOME BY A HUMAN CELL COMPONENT(S)
    BRODER, CC
    DIMITROV, DS
    BLUMENTHAL, R
    BERGER, EA
    [J]. VIROLOGY, 1993, 193 (01) : 483 - 491
  • [7] SYNERGY BETWEEN HUMAN MONOCLONAL-ANTIBODIES TO HIV EXTENDS THEIR EFFECTIVE BIOLOGIC ACTIVITY AGAINST HOMOLOGOUS AND DIVERGENT STRAINS
    BUCHBINDER, A
    ZOLLAPAZNER, S
    KARWOWSKA, S
    GORNY, MK
    BURDA, ST
    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 1992, 8 (08) : 1395 - 1395
  • [8] BUGELSKI PJ, 1991, J ACQ IMMUN DEF SYND, V4, P923
  • [9] THE REGION OF THE ENVELOPE GENE OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 RESPONSIBLE FOR DETERMINATION OF CELL TROPISM
    CANN, AJ
    CHURCHER, MJ
    BOYD, M
    OBRIEN, W
    ZHAO, JQ
    ZACK, J
    CHEN, ISY
    [J]. JOURNAL OF VIROLOGY, 1992, 66 (01) : 305 - 309
  • [10] HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 T-CELL TROPISM IS DETERMINED BY EVENTS PRIOR TO PROVIRUS FORMATION
    CANN, AJ
    ZACK, JA
    GO, AS
    ARRIGO, SJ
    KOYANAGI, Y
    GREEN, PL
    KOYANAGI, Y
    PANG, S
    CHEN, ISY
    [J]. JOURNAL OF VIROLOGY, 1990, 64 (10) : 4735 - 4742
123456789