2′-O-dimethylaminoethoxyuridine and 5-dimethylaminopropargyl deoxyuridine for at base pair recognition in triple helices

被引：5

作者：

Brennan, Lavinia ^{[1
]}

Peng, Guomei ^{[1
]}

Srinivasan, Natarajan ^{[1
]}

Fox, Keith R. ^{[2
]}

Brown, Tom ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

[2] Univ Southampton, Sch Biol Sci, Southampton, Hants, England

来源：

NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2007年 / 26卷 / 10-12期

基金：

英国生物技术与生命科学研究理事会;

关键词：

antigene; triple helices; triplexes; AT recognition;

D O I：

10.1080/15257770701530525

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nucleoside analogues 2-O-dimethylaminoethoxy uridine and 5-dimethylaminopropargyl deoxyuridine have been synthesised and incorporated into oligonucteotides.. Their triplex-stabilising properties have been determined in fluorescence melting experiments.

引用

页码：1283 / 1286

页数：4

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