Trigonella foenum graecum (Fenugreek) seed extract as an antineoplastic agent

被引：82

作者：

Sur, P

Das, M

Gomes, A

Vedasiromoni, JR

Sahu, NP

Banerjee, S

Sharma, RM

Ganguly, DK

机构：

[1] Indian Inst Chem Biol, Div Pharmacol & Expt Therapeut, Kolkata 700032, W Bengal, India

[2] Indian Inst Chem Biol, Div Steroid & Terpenoid Chem, Kolkata 700032, W Bengal, India

来源：

PHYTOTHERAPY RESEARCH | 2001年 / 15卷 / 03期

关键词：

Trigonella foenum graecum; fenugreek; Ehrlich ascites carcinoma; antineoplastic;

D O I：

10.1002/ptr.718

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The antineoplastic effect of Trigonella foenum graecum seed extract has been evaluated in the Ehrlich ascites carcinoma (EAC) model in Balb-C mice. Intra-peritoneal administration of the alcohol extract of the seed both before and after inoculation of EAC cell in mice produced more than 70% inhibition of tumour cell growth with respect to the control. Treatment with the extract was found to enhance both the peritoneal exudate cell and macrophage cell counts, The extract also produced a significant antiinflammatory effect. We report here the antiinflammatory and antineoplastic effects, of Trigonella foenum graecum seed extract. Copyright (C) 2001 John Whey & Sons, Ltd.

引用

页码：257 / 259

页数：3