Signaling pathways activated by the growth hormone receptor

被引：264

作者：

Herrington, J ^{[1
]}

Carter-Su, C ^{[1
]}

机构：

[1] Univ Michigan, Sch Med, Dept Physiol, Ann Arbor, MI 48109 USA

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 2001年 / 12卷 / 06期

关键词：

D O I：

10.1016/S1043-2760(01)00423-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In recent years, significant progress has been made in elucidating the signaling pathways activated by the growth hormone (GH) receptor. An initiating event is probably the activation of JAK2 (Janus kinase 2). a on receptor-associated tyrosine kinase. Identification of the proteins recruited to the GH receptor-JAK2 complex and dissection of the signaling pathways that are subsequently activated will ultimately provide a basis for understanding GH action at the molecular level.

引用

页码：252 / 257

页数：6

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