Laboratory diagnosis of autoimmune cytopenias

被引:8
作者
Manny, N
Zelig, O
机构
[1] Hadassah Med Org, Blood Bank, IL-91120 Jerusalem, Israel
[2] Hadassah Med Org, Dept Transfus Med, IL-91120 Jerusalem, Israel
关键词
D O I
10.1097/00062752-200011000-00016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The past year's literature shows that little progress has been achieved in the laboratory diagnosis. of autoimmune hemolytic. anemia. The direct antiglobulin test is the only diagostic test for autoimmune hemolytic anemia. Advantages of new techniques, such as the gel test, have to be determined. Today, cephalosporins are known to cause both drug-dependent and -independent autoantibodies. The diagnosis of idiopathic thrombocytopenic purpura is a clinical one. The new assays that measure antibodies against specific glycoproteins offer improved specificity. New laboratory advancements and accumulation of data on granylocytes' antigens and antibodies enabled us to recommend guidelines for the laboratory investigation. of autoimmune neutropenia. Curr Opin Hematol 2000, 7:414-419 (C) 2000 Lippincott Williams & Wilkins, Inc.
引用
收藏
页码:414 / 419
页数:6
相关论文
共 36 条
  • [11] ANALYSIS OF GRANULOCYTE-REACTIVE ANTIBODIES USING AN IMMUNOASSAY BASED UPON MONOCLONAL-ANTIBODY-SPECIFIC IMMOBILIZATION OF GRANULOCYTE ANTIGENS
    BUX, J
    KOBER, B
    KIEFEL, V
    MUELLERECKHARDT, C
    [J]. TRANSFUSION MEDICINE, 1993, 3 (02) : 157 - 162
  • [12] The use of allele-specific recombinant Fcγ receptor IIIb antigens for the detection of granulocyte antibodies
    Bux, J
    Kissel, K
    Hofmann, C
    Santoso, S
    [J]. BLOOD, 1999, 93 (01) : 357 - 362
  • [13] COOMBS RRA, 1945, BRIT J EXP PATHOL, V26, P255
  • [14] Historical note: Past, present and future of the antiglobulin test
    Coombs, RRA
    [J]. VOX SANGUINIS, 1998, 74 (02) : 67 - 73
  • [15] High pathogenic potential of low-affinity autoantibodies in experimental autoimmune hemolytic anemia
    Fossati-Jimack, L
    Reininger, L
    Chicheportiche, Y
    Clynes, R
    Ravetch, JV
    Honjo, T
    Izui, S
    [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 190 (11) : 1689 - 1696
  • [16] Idiopathic thrombocytopenic purpura: A practice guideline developed by explicit methods for the American Society of Hematology
    George, JN
    Woolf, SH
    Raskob, GE
    Wasser, JS
    Aledort, LM
    Ballem, PJ
    Blanchette, VS
    Bussel, JB
    Cines, DB
    Kelton, JG
    Lichtin, AE
    McMillan, R
    Okerbloom, JA
    Regan, DH
    Warrier, I
    [J]. BLOOD, 1996, 88 (01) : 3 - 40
  • [17] Idiopathic thrombocytopenic purpura: a guideline for diagnosis and management of children and adults
    George, JN
    Woolf, SH
    Raskob, GE
    [J]. ANNALS OF MEDICINE, 1998, 30 (01) : 38 - 44
  • [18] Immune thrombocytopenic purpura in adults: clinical aspects
    Gillis, S
    Eldor, A
    [J]. BAILLIERES CLINICAL HAEMATOLOGY, 1998, 11 (02): : 361 - 372
  • [19] HE RY, 1994, BLOOD, V83, P1024
  • [20] HUIZINGA TWJ, 1990, BLOOD, V75, P213