Immunomodulators for prevention and treatment of infectious diseases in food-producing animals

被引:30
作者
Blecha, F [1 ]
机构
[1] Kansas State Univ, Coll Vet Med, Dept Anat & Physiol, Manhattan, KS 66506 USA
关键词
D O I
10.1016/S0749-0720(15)30010-4
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The goal of immunomodulation in food-producing animals is to regulate immunity for the benefit of the animal and production efficiency. Immunomodulators are substances that exert this control and include cytokines, pharmaceuticals, microbial products, nutraceuticals, and traditional medicinal plants. Although treatment and prevention of infectious diseases are the most common reasons to use immunomodulators, other conditions, such as amelioration of stress-induced immunosuppression, maturation of the neonate's developing immune response, and strategies to reduce the metabolic cost of eliciting an immune response also are well suited for immunomodulation. Continued discovery of new immune regulators and increased understanding of immunity in food-producing animals will ensure new opportunities for the use of immunomodulators in food-producing animals.
引用
收藏
页码:621 / +
页数:14
相关论文
共 88 条
[21]   The use of immunomodulators in the control of infectious bovine rhinotracheitis [J].
Castrucci, G ;
Osburn, BI ;
Frigeri, F ;
Ferrari, M ;
Salvatori, D ;
Lo Dico, M ;
Barreca, F .
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 2000, 23 (03) :163-173
[22]  
Charley B., 1993, Sciences Veterinaires Medecine Comparee, V95, P195
[23]  
Charley B., 1991, Point Veterinaire, V23, P731
[24]   GLUCAN ADMINISTRATION POTENTIATES IMMUNE DEFENSE-MECHANISMS OF CHANNEL CATFISH, ICTALURUS-PUNCTATUS RAFINESQUE [J].
CHEN, D ;
AINSWORTH, AJ .
JOURNAL OF FISH DISEASES, 1992, 15 (04) :295-304
[25]  
Chew BP, 1997, ANTICANCER RES, V17, P1099
[26]  
Cook ME, 1999, ADV VETER MED AP, V41, P53
[27]   IMMUNE MODULATION BY ALTERED NUTRIENT METABOLISM - NUTRITIONAL CONTROL OF IMMUNE-INDUCED GROWTH DEPRESSION [J].
COOK, ME ;
MILLER, CC ;
PARK, Y ;
PARIZA, M .
POULTRY SCIENCE, 1993, 72 (07) :1301-1305
[28]   ORAL TREATMENT OF TRANSMISSIBLE GASTROENTERITIS WITH NATURAL HUMAN INTERFERON-ALPHA - A FIELD-STUDY [J].
CUMMINS, JM ;
MOCK, RE ;
SHIVE, BW ;
KRAKOWKA, S ;
RICHARDS, AB ;
HUTCHESON, DP .
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1995, 45 (3-4) :355-360
[29]   In vivo macrophage activation in chickens with Acemannan, a complex carbohydrate extracted from Aloe vera [J].
Djeraba, A ;
Quere, P .
INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 2000, 22 (05) :365-372
[30]  
Dritz SS, 1996, J AM VET MED ASSOC, V208, P711