Is it possible to construct phylogenetic trees using polypeptide hormone sequences?

被引：74

作者：

Dores, RM ^{[1
]}

Rubin, DA ^{[1
]}

Quinn, TW ^{[1
]}

机构：

[1] HARVARD UNIV,MASSACHUSETTS GEN HOSP,SCH MED,ENDOCRINE UNIT,BOSTON,MA 02114

来源：

GENERAL AND COMPARATIVE ENDOCRINOLOGY | 1996年 / 103卷 / 01期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1006/gcen.1996.0088

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Because of the high degree of primary sequence conservation in neuropeptides and low molecular weight polypeptide hormones, these polypeptides are not useful for constructing phylogenetic trees based on maximum parsimony analysis. This review focuses on the organization of neuropeptide and polypeptide hormone precursors and discusses strategies for aligning polypeptide precursors for phylogenetic analysis. Examples are provided to support the hypothesis that some neuropeptide and polypeptide precursors and some high molecular weight polypeptide hormones can be used as data sets for resolving deep divergences among vertebrate taxa. (C) 1995 Academic Press, Inc.

引用

页码：1 / 12

页数：12

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