Automated batch scale-up of microwave-promoted Suzuki and Heck coupling reactions in water using ultra-low metal catalyst concentrations

被引：91

作者：

Arvela, RK

Leadbeater, NE

Collins, MJ

机构：

[1] Univ Connecticut, Dept Chem, Storrs, CT 06269 USA

[2] CEM Microwave Technol, Matthews, NC 28104 USA

来源：

TETRAHEDRON | 2005年 / 61卷 / 39期

关键词：

microwave; water; Suzuki;

D O I：

10.1016/j.tet.2005.07.063

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Representative Suzuki and Heck couplings in water using ultra-low catalyst concentrations have been scaled-up using an automated batch stop-flow microwave apparatus. Our scale-up methodology shows proof of concept and is easy, fast and cheap to run. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：9349 / 9355

页数：7

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