Role of cell-cycle regulators in lung cancer

被引：33

作者：

Caputi, M

Russo, G

Esposito, V

Mancini, A

Giordano, A

机构：

[1] Temple Univ, Coll Sci & Technol, Ctr Biotechnol, Sbarro Inst Canc Res & Mol Med, Philadelphia, PA 19122 USA

[2] Univ Naples 2, Dept Cardiothorac Sci, Naples, Italy

[3] Div AOB 3, Naples, Italy

[4] Univ Siena, Dept Human Pathol & Oncol, I-53100 Siena, Italy

来源：

JOURNAL OF CELLULAR PHYSIOLOGY | 2005年 / 205卷 / 03期

关键词：

D O I：

10.1002/jcp.20424

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Lung cancer is the leading cause of cancer death worldwide. Histologically, 80% of lung cancers are classified as non-small-cell lung cancer (NSCLC), and the remaining 20% as small-cell lung cancer (SCLC). Lung carcinoma is the result of molecular changes in the cell, resulting in the deregulation of pathways controlling normal cellular growth, differentiation, and apoptosis. This review summarizes some of the most recent findings about the role of cell-cycle proteins in lung cancer pathogenesis and progression.

引用

页码：319 / 327

页数：9

共 105 条

[1] The p53 network
Agarwal, ML
Taylor, WR
Chernov, MV
Chernova, OB
Stark, GR
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (01) : 1 - 4
[2] Baldi A, 1996, CLIN CANCER RES, V2, P1239
[3] Baldi A, 1997, CLIN CANCER RES, V3, P1691
[4] Identification of genes over-expressed in small cell lung carcinoma using suppression subtractive hybridization and cDNA microarray expression analysis
Bangur, CS
Switzer, A
Fan, LQ
Marton, MJ
Meyer, MR
Wang, TT
[J]. ONCOGENE, 2002, 21 (23) : 3814 - 3825
[5] Gene-expression profiles predict survival of patients with lung adenocarcinoma
Beer, DG
Kardia, SLR
Huang, CC
Giordano, TJ
Levin, AM
Misek, DE
Lin, L
Chen, GA
Gharib, TG
Thomas, DG
Lizyness, ML
Kuick, R
Hayasaka, S
Taylor, JMG
Iannettoni, MD
Orringer, MB
Hanash, S
[J]. NATURE MEDICINE, 2002, 8 (08) : 816 - 824
[6] Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
Bhattacharjee, A
Richards, WG
Staunton, J
Li, C
Monti, S
Vasa, P
Ladd, C
Beheshti, J
Bueno, R
Gillette, M
Loda, M
Weber, G
Mark, EJ
Lander, ES
Wong, W
Johnson, BE
Golub, TR
Sugarbaker, DJ
Meyerson, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (24) : 13790 - 13795
[7] CYCLIN PCNA IS THE AUXILIARY PROTEIN OF DNA POLYMERASE-DELTA
BRAVO, R
FRANK, R
BLUNDELL, PA
MACDONALDBRAVO, H
[J]. NATURE, 1987, 326 (6112) : 515 - 517
[8] p21waf1/cip1mda-6 expression in non-small-cell lung cancer:: Relationship to survival
Caputi, M
Esposito, V
Baldi, A
De Luca, A
Dean, C
Signoriello, G
Baldi, F
Giordano, A
[J]. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1998, 18 (02) : 213 - 217
[9] Chang TH, 2002, CLIN CANCER RES, V8, P1206
[10] Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas
Chen, G
Wang, H
Gharib, TG
Huang, CC
Thomas, DG
Shedden, KA
Kuick, R
Taylor, JMG
Kardia, SLR
Misek, DE
Giordano, TJ
Iannettoni, MD
Orringer, MB
Hanash, SM
Beer, DG
[J]. MOLECULAR & CELLULAR PROTEOMICS, 2003, 2 (02) : 107 - 116

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