Genes involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide in Streptococcus mutans

被引:54
作者
Yamashita, Y [1 ]
Tsukioka, Y [1 ]
Tomihisa, K [1 ]
Nakano, Y [1 ]
Koga, T [1 ]
机构
[1] Kyushu Univ, Fac Dent, Dept Prevent Dent, Fukuoka 8128582, Japan
关键词
D O I
10.1128/JB.180.21.5803-5807.1998
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We identified in Streptococcus mutans six new genes (rgpA through rgpF), whose disruption results in a loss of serotype-specific antigenicity, specified by the glucose side chains of rhamnose-glucose polysaccharide from the cell wall. Rhamnose and glucose content of the cell wall decreased drastically in all these disruption mutants, except that in the rgpE mutant only the glucose content decreased. RgpC and RgpD are homologous to ATP-binding cassette transporter components and may be involved in polysaccharide export, whereas RgpE may be a transferase of side chain glucose.
引用
收藏
页码:5803 / 5807
页数:5
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