Ruthenium-Catalyzed Oxidative Synthesis of 2-Pyridones through C-H/N-H Bond Functionalizations

被引：189

作者：

Ackermann, Lutz ^{[1
]}

Lygin, Alexander V. ^{[1
]}

Hofmann, Nora ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 12期

关键词：

CARBON-CARBON BONDS; DIRECT ARYLATIONS; COUPLING REACTIONS; INTERNAL ALKYNES; BENZOIC-ACIDS; PALLADIUM; CONSTRUCTION; ACTIVATION; MULTIPLE; HYDROGEN;

D O I：

10.1021/ol201244s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An Inexpensive ruthenium catalyst enabled oxidative annulations of alkynes by acrylamides with ample scope, which allowed for the preparation of 2-pyridones employing various electron-rich and electron-deficient acrylamides as well as (di)aryl- and (di)alkyl-substituted alkynes.

引用

页码：3278 / 3281

页数：4

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