The developmental role of microRNA in plants

被引:304
作者
Kidner, CA
Martienssen, RA [1 ]
机构
[1] Univ Edinburgh, Inst Mol Plant Sci, Edinburgh EH3 5LR, Midlothian, Scotland
[2] Royal Bot Gardens, Edinburgh EH3 5LR, Midlothian, Scotland
[3] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/j.pbi.2004.11.008
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
MicroRNAs (miRNAs) are single-stranded RNA molecules of around 22 nucleotides (nt) in length that are associated with the RNA-induced silencing complex (RISC). They play an important role in plant development, either by targeting mRNA for cleavage or by inhibiting translation. Over the past year, the list of known miRNAs, confirmed targets and developmental effects has expanded, as has the realization that they are conserved during evolution and that small RNAs can play a direct role in cell-cell signaling.
引用
收藏
页码:38 / 44
页数:7
相关论文
共 74 条
  • [1] Modulation of floral development by a gibberellin-regulated microRNA
    Achard, P
    Herr, A
    Baulcombe, DC
    Harberd, NP
    [J]. DEVELOPMENT, 2004, 131 (14): : 3357 - 3365
  • [2] Genes involved in organ separation in Arabidopsis: An analysis of the cup-shaped cotyledon mutant
    Aida, M
    Ishida, T
    Fukaki, H
    Fujisawa, H
    Tasaka, M
    [J]. PLANT CELL, 1997, 9 (06) : 841 - 857
  • [3] Aida M, 1999, DEVELOPMENT, V126, P1563
  • [4] Regulation of flowering time and floral organ identity by a microRNA and its APETALA2-like target genes
    Aukerman, MJ
    Sakai, H
    [J]. PLANT CELL, 2003, 15 (11) : 2730 - 2741
  • [5] MicroRNAs: Genomics, biogenesis, mechanism, and function (Reprinted from Cell, vol 116, pg 281-297, 2004)
    Bartel, David P.
    [J]. CELL, 2007, 131 (04) : 11 - 29
  • [6] BARTEL DP, 2004, IN PRESS NATURE REV, V5
  • [7] Role for a bidentate ribonuclease in the initiation step of RNA interference
    Bernstein, E
    Caudy, AA
    Hammond, SM
    Hannon, GJ
    [J]. NATURE, 2001, 409 (6818) : 363 - 366
  • [8] AGO1 defines a novel locus of Arabidopsis controlling leaf development
    Bohmert, K
    Camus, I
    Bellini, C
    Bouchez, D
    Caboche, M
    Benning, C
    [J]. EMBO JOURNAL, 1998, 17 (01) : 170 - 180
  • [9] Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    Bohnsack, MT
    Czaplinski, K
    Görlich, D
    [J]. RNA, 2004, 10 (02) : 185 - 191
  • [10] HASTY, the Arabidopsis ortholog of exportin 5/MSN5, regulates phase change and morphogenesis
    Bollman, KM
    Aukerman, MJ
    Park, MY
    Hunter, C
    Berardini, TZ
    Poethig, RS
    [J]. DEVELOPMENT, 2003, 130 (08): : 1493 - 1504