Viral therapy for glioblastoma

被引：29

作者：

Chiocca, EA ^{[1
]}

Aghi, M ^{[1
]}

Fulci, G ^{[1
]}

机构：

[1] Massachusetts Gen Hosp E, Mol Neurooncol Lab, Neurosurg Serv, Charlestown, MA 02129 USA

来源：

CANCER JOURNAL | 2003年 / 9卷 / 03期

关键词：

D O I：

10.1097/00130404-200305000-00005

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Malignant gliomas remain amongst the most difficult cancer to treat. Viral-based gene therapies have been employed for the last decade in preclinical and clinical modes as a novel treatment modality. In this review, such therapies are summarized. The overwhelming majority of clinical studies point one to conclude that methodologies that will increase tumor infection/transduction will lead to enhanced therapeutic results.

引用

页码：167 / 179

页数：13

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