Lewis acid promoted alkynylation of imines with terminal alkynes: simple, mild and efficient preparation of propargylic amines

被引:66
作者
Jiang, B [1 ]
Si, YG [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China
关键词
alkynylation; imine; propargylic amine; Lewis acid;
D O I
10.1016/S0040-4039(03)01674-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A mild and efficient addition of terminal alkynes to imines in the presence of ZnCl2, Et3N and TMSCl gives propargylamines in good yields. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:6767 / 6768
页数:2
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