Transplantation of unrelated cord blood cells

被引:40
作者
Weinreb, S
Delgado, JC
Clavijo, OP
Yunis, EJ
Bayer-Zwirello, L
Polanski, L
Deluhery, L
Cohn, G
Yao, JT
Stec, TC
Higby, D
Andrzejewski, C
机构
[1] Baystate Med Ctr, Dept Pathol, Transfus Med Serv, Springfield, MA 01199 USA
[2] Baystate Med Ctr, Dept Med, Springfield, MA 01199 USA
[3] Baystate Med Ctr, Dept OB GYN, Springfield, MA 01199 USA
[4] Dana Farber Canc Inst, Dept Canc Immunol & AIDS, Boston, MA 02115 USA
关键词
placental blood; unmatched; multiple donors; CML;
D O I
10.1038/sj.bmt.1701309
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A 43-year-old woman with Philadelphia chromosome (Ph) positive chronic myelogenous leukemia in acute phase received high-dose chemotherapy followed by transfusion of 12 randomly selected units of umbilical cord blood. HLA analysis showed cells of one donor from day +10 to day +43 post-transfusion. This unit was HLA class II identical with that of the patient.
引用
收藏
页码:193 / 196
页数:4
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