Total synthesis of 3-azasteroids via the transannular Diels-Alder strategy

被引：7

作者：

Fortin, D ^{[1
]}

Gaudette, F ^{[1
]}

Marsault, E ^{[1
]}

Deslongchamps, P ^{[1
]}

机构：

[1] Univ Sherbrooke, Inst Pharmacol Sherbrooke, Organ Synth Lab, Sherbrooke, PQ J1H 5N4, Canada

来源：

TETRAHEDRON | 2001年 / 57卷 / 19期

基金：

加拿大自然科学与工程研究理事会;

关键词：

3-azasteroids; transannular Diels-Alder strategy; acyclic trienes;

D O I：

10.1016/S0040-4020(01)00290-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total synthesis of four new 3-azasteroids is described, using the transannular Diels-Alder (TADA) reaction. Elaboration of the acyclic trienes, macrocyclizations and TADA reactions are detailed, as well as the stereochemical outcome of the reaction. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4167 / 4177

页数：11

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