Analytical methods applied to the determination of heterocyclic aromatic amines in foods

被引：80

作者：

Sanz Alaejos, M. ^{[1
]}

Ayala, J. H. ^{[1
]}

Gonzalez, V. ^{[1
]}

Afonso, A. M. ^{[1
]}

机构：

[1] Univ La Laguna, Dept Analyt Chem Nutr & Food Sci, San Cristobal la Laguna 38205, Santa Cruz De T, Spain

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2008年 / 862卷 / 1-2期

关键词：

heterocyclic aromatic amines; foods; extraction methods; chromatographic methods/mass spectrometry; capillary electrophoresis;

D O I：

10.1016/j.jchromb.2007.11.040

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Analytical aspects concerning the heterocyclic aromatic amines (HAAs) determination in foods are reviewed. Sample pre-treatment procedures such as liquid-liquid extraction (LLE), supercritical fluid extraction, solid-phase extraction (SPE), solid-phase microextraction (SPME), and the mainly used LLE-SPE tandem extraction are discussed. The analytical methods used for the identification and quantification are HPLC, HPLC combined with single or tandem MS detection (HPLC-MS, HPLC-MS/MS), GC-MS and capillary electrophoresis. Advantages and figures of merit for each technique are discussed. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：15 / 42

页数：28

共 144 条

[1] Heterocyclic amines in fresh and processed meat products [J].

Abdulkarim, BG ;

Smith, JS .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (11) :4680-4687

[2] Exposure to heterocyclic aromatic amines from the consumption of cooked red meat and its effect on human cancer risk: A review [J].

Alaejos, M. S. ;

Gonzalez, V. ;

Afonso, A. M. .

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2008, 25 (01) :2-24

[3]

ALAEJOS MS, UNPUN CHEM REV

[4]

ALAEJOS MS, UNPUB FOOD ADDIT CON

[5]

[Anonymous], 1993, IARC MON EV CARC RIS

[6] Formation of heterocyclic amines in a meat juice model system [J].

Arvidsson, P ;

van Boekel, MAJS ;

Skog, K ;

Solyakov, A ;

Jägerstad, M .

JOURNAL OF FOOD SCIENCE, 1999, 64 (02) :216-221

[7] Kinetics of formation of polar heterocyclic amines in a meat model system [J].

Arvidsson, P ;

vanBoekel, MAJS ;

Skog, K ;

Jagerstad, M .

JOURNAL OF FOOD SCIENCE, 1997, 62 (05) :911-916

[8] Blue Chitin columns for the extraction of heterocyclic amines from urine samples [J].

Bång, J ;

Frandsen, H ;

Skog, K .

CHROMATOGRAPHIA, 2004, 60 (11-12) :651-655

[9] Blue Chitin columns for the extraction of heterocyclic amines from cooked meat [J].

Bång, J ;

Nukaya, H ;

Skog, K .

JOURNAL OF CHROMATOGRAPHY A, 2002, 977 (01) :97-105

[10] Ultra-performance liquid chromatography-tandem mass spectrometry for the analysis of heterocyclic amines in food [J].

Barcelo-Barrachina, E. ;

Moyano, E. ;

Galceran, M. T. ;

Lliberia, J. L. ;

Bago, B. ;

Cortes, M. A. .

JOURNAL OF CHROMATOGRAPHY A, 2006, 1125 (02) :195-203

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