Partial Androgen Deficiency, Depression, and Testosterone Supplementation in Aging Men

被引：35

作者：

Amore, Mario ^{[1
]}

Innamorati, Marco ^{[1
]}

Costi, Sara ^{[1
]}

Sher, Leo ^{[2
]}

Girardi, Paolo ^{[3
]}

Pompili, Maurizio ^{[3
]}

机构：

[1] Univ Parma, Inst Psychiat, Dept Neurosci, I-43100 Parma, Italy

[2] Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA

[3] Univ Roma La Sapienza, St Andrea Hosp, Suicide Prevent Ctr, Dept Neurosci Mental Hlth & Sensory Organs, I-00189 Rome, Italy

来源：

INTERNATIONAL JOURNAL OF ENDOCRINOLOGY | 2012年 / 2012卷

关键词：

LATE-ONSET HYPOGONADISM; IMPROVES SEXUAL FUNCTION; QUALITY-OF-LIFE; OLDER MEN; ELDERLY-MEN; BIOAVAILABLE TESTOSTERONE; REPLACEMENT THERAPY; EXOGENOUS TESTOSTERONE; TRANSDERMAL TESTOSTERONE; VISUOSPATIAL COGNITION;

D O I：

10.1155/2012/280724

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this review was to summarize current knowledge on the correlation between depressive symptoms with a syndrome called partial androgen deficiency of the aging male (PADAM) and on the potential benefits of testosterone (T) treatment on mood. Despite, the causative nature of the relationship between low T levels and depression is uncertain, many hypogonadal men suffer from depression and vice versa several depressed patients are affected by hypogonadism. Supplementation with testosterone failed to show sound evidence of effectiveness in the treatment of depression. Nevertheless, testosterone supplementation has proved to be effective on some domains significant for the quality of life of aged patients with PADAM (sexual function and cognitive functions, muscular strengths).

引用

页数：17

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