Phagocytosis by neutrophils

被引：267

作者：

Lee, WL

Harrison, RE

Grinstein, S

机构：

[1] Hosp Sick Children, Div Cell Biol, Cell Biol Program, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Dept Biochem, Toronto, ON M5G 1X8, Canada

[3] Univ Toronto, Dept Life Sci, Scarborough, ON M1C 1A4, Canada

[4] Univ Toronto, Dept Med, Div Respirol, Toronto, ON M5G 1X8, Canada

[5] Univ Toronto, Interdepartmental Div Crit Care Med, Toronto, ON M5G 1X8, Canada

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 14期

关键词：

phagosome; endosome; lysosome; acidification; microbial killing; oxidase; actin remodeling;

D O I：

10.1016/j.micinf.2003.09.014

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation and maturation in neutrophils. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：1299 / 1306

页数：8

共 44 条

[1] Perspectives on the identity of the H+ channel involved in the respiratory burst [J].