Asymmetric synthesis of (2R,3S)-2,3-epoxyamides via camphor-derived sulfonium ylides

被引：43

作者：

Zhou, YG ^{[1
]}

Hou, XL ^{[1
]}

Dai, LX ^{[1
]}

Xia, LJ ^{[1
]}

Tang, MH ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 01期

关键词：

D O I：

10.1039/a806189k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiomerically enriched trans-2,3-epoxyamides 3 were prepared by the reaction of aldehydes 2 with camphor-derived chiral sulfonium ylide 1 in good yields and moderate to good ee values. The absolute configuration of the reaction product is also determined by chemical transformations.

引用

页码：77 / 80

页数：4

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