TiCl3/PhN2+-mediated radical addition of ethers to aldimines generated in situ under aqueous conditions

被引：26

作者：

Clerici, A

Cannella, R

Panzeri, W

Pastori, N

Regolini, E

Porta, O

机构：

[1] Politecn Milan, Dipartimento Chim Mat & Ingn Chim Giulio Natta, Sez Chim, I-20131 Milan, Italy

[2] Politecn Milan, CNR, Ist Chim Riconoscimento Mol, Sez A Quilico, I-20131 Milan, Italy

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 48期

关键词：

titanium trichloride; one-electron reduction; radical addition; aldimines; three-component reaction;

D O I：

10.1016/j.tetlet.2005.09.158

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ti(III)-mediated one-electron reduction of phenyldiazonium cation, followed by phenyl radical alpha-H atom abstraction from ethers, leads to one-pot radical addition of ethers to the C-atom of imines generated in situ from the corresponding aldehydes and imines under aqueous conditions. The reaction is not limited to aromatic aldehydes and may be applied to imines generated in situ from formaldehyde and enolizable aldehydes. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：8351 / 8354

页数：4

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