Antigen presentation - A protease draws first blood

被引：17

作者：

Bogyo, M ^{[1
]}

Ploegh, HL ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

来源：

NATURE | 1998年 / 396卷 / 6712期

关键词：

D O I：

10.1038/25238

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Foreign proteins in a cell are chopped up and presented to the immune system by molecules of the major histocompatibility complex. What enzymes are responsible for making these cuts? The enzyme that delivers the initial blow specifically to the tetanus toxin has now been identified as asparaginyl endopeptidase.

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页码：625 / +

页数：2

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