Analysis of drugs and personal care products in French source and drinking waters: the analytical challenge and examples of application

被引:43
作者
Bruchet, A [1 ]
Hochereau, C [1 ]
Picard, C [1 ]
Decottignies, V [1 ]
Rodrigues, JM [1 ]
Janex-Habibi, ML [1 ]
机构
[1] CIRSEE, Suez Environm, F-78230 Le Pecq, France
关键词
antibiotics; surface waters; drugs; musks; X-ray contrast media;
D O I
10.2166/wst.2005.0224
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
This paper illustrates the challenge faced by analytical chemists when trying to measure selected compounds representative of various classes of prescription and hospital drugs. Because hundreds of drugs belonging to a wide variety of chemical groups are allowed for use, an array of analytical methods has to be implemented. As an example, as part of the European Poseidon Project, five different methods were required to measure eight drugs and personal care products. These methods are discussed in detail. Examples of application to surface and ground waters from the Paris area are also reported. The antibiotics roxithromycin and sulfamethoxazole were detected for the first time in the Seine River downstream of Paris. The behaviour of the eight target compounds during aquifer recharge and drinking water treatment is described. An incident involving the detection of micrograms per litre levels of the personal care product Galaxolide in a drinking water distribution system is reported. The value of the pharmaceuticals and personal care products selected as potential indicators is also discussed.
引用
收藏
页码:53 / 61
页数:9
相关论文
共 11 条
[1]   Carbamazepine as a possible anthropogenic marker in the aquatic environment: investigations on the behaviour of Carbamazepine in wastewater treatment and during groundwater infiltration [J].
Clara, M ;
Strenn, B ;
Kreuzinger, N .
WATER RESEARCH, 2004, 38 (04) :947-954
[2]   Pharmaceuticals and personal care products in the environment: Agents of subtle change? [J].
Daughton, CG ;
Ternes, TA .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1999, 107 :907-938
[3]  
Heberer T, 1997, FRESEN ENVIRON BULL, V6, P438
[4]  
Heberer T., 1996, VOM WASSER, V86, P19
[5]  
JANEX ML, 2003, IWA LEAD ED C NOORDW, P29
[6]  
Mons M.N., 2003, 2003040 BTO KIW WAT
[7]  
SACHER F, 2001, PHARM GROUNDWATERS A
[8]  
Ternes T.A., 2001, ACS S SERIES, V791
[9]   Analysis of endocrine disruptors, pharmaceuticals, and personal care products in water using liquid chromatography/tandem mass spectrometry [J].
Vanderford, BJ ;
Pearson, RA ;
Rexing, DJ ;
Snyder, SA .
ANALYTICAL CHEMISTRY, 2003, 75 (22) :6265-6274
[10]  
VERSTEEGH JFM, 2003, 7037190042003 RIVM