Photoacoustic Doppler flow measurement in optically scattering media

被引:55
作者
Fang, Hui [1 ]
Maslov, Konstantin [1 ]
Wang, Lihong V. [1 ]
机构
[1] Washington Univ, Opt Imaging Lab, Dept Biomed Engn, St Louis, MO 63130 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1063/1.2825569
中图分类号
O59 [应用物理学];
学科分类号
摘要
We recently observed the photoacoustic Doppler effect from flowing small light-absorbing particles. Here, we apply the effect to measure blood-mimicking fluid flow in an optically scattering medium. The light scattering in the medium decreases the amplitude of the photoacoustic Doppler signal but does not affect either the magnitude or the directional discrimination of the photoacoustic Doppler shift. This technology may hold promise for a new Doppler method for measuring blood flow in microcirculation with high sensitivity. (c) 2007 American Institute of Physics.
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页数:3
相关论文
共 17 条
[11]   The effect of multiple scattering on velocity profiles measured using Doppler OCT [J].
Moger, J ;
Matcher, SJ ;
Winlove, CP ;
Shore, A .
JOURNAL OF PHYSICS D-APPLIED PHYSICS, 2005, 38 (15) :2597-2605
[12]  
Staveren H.J.V., 1991, APPL OPTICS, V30, P4507
[13]   PROPERTIES OF PHOTON DENSITY WAVES IN MULTIPLE-SCATTERING MEDIA [J].
TROMBERG, BJ ;
SVAASAND, LO ;
TSAY, TT ;
HASKELL, RC .
APPLIED OPTICS, 1993, 32 (04) :607-616
[14]  
Wang L.V., 2007, BIOMEDICAL OPTICS PR, P343
[15]   LOCALIZED FLUID FLOW MEASUREMENTS WITH AN HE-NE LASER SPECTROMETER1 ( E ) [J].
YEH, Y ;
CUMMINS, HZ .
APPLIED PHYSICS LETTERS, 1964, 4 (10) :176-&
[16]   In vivo volumetric imaging of subcutaneous microvasculature by photoacoustic microscopy [J].
Zhang, Hao F. ;
Maslov, Konstantin ;
Li, Meng-Lin ;
Stoica, George ;
Wang, Lihong V. .
OPTICS EXPRESS, 2006, 14 (20) :9317-9323
[17]   Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging [J].
Zhang, Hao F. ;
Maslov, Konstantin ;
Stoica, George ;
Wang, Lihong V. .
NATURE BIOTECHNOLOGY, 2006, 24 (07) :848-851