Secondary structure in oligomers of carbohydrate amino acids

被引:99
作者
Smith, MD
Claridge, TDW
Tranter, GE
Sansom, MSP
Fleet, GWJ
机构
[1] Univ Oxford, Dyson Perrins Lab, Oxford OX1 3QY, England
[2] GlaxoWellcome Ltd, Stevenage SG1 2NY, Herts, England
[3] Univ Oxford, Mol Biophys Lab, Oxford OX1 3QU, England
关键词
D O I
10.1039/a805401k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Short oligomeric chains of tetrahydrofuran amino acids exhibit a novel repeating beta-turn type secondary structure in solution stabilised by hydrogen bonds and provide clear evidence that carbopeptoids will allow control of conformation in peptidomimetics.
引用
收藏
页码:2041 / 2042
页数:2
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