Do CARs Need a Driver's License? Adoptive Cell Therapy with Chimeric Antigen Receptor-Redirected T Cells Has Caused Serious Adverse Events

被引：20

作者：

Buening, Hildegard ^{[1
,2
]}

Uckert, Wolfgang ^{[3
]}

Cichutek, Klaus ^{[4
]}

Hawkins, Robert E. ^{[5
]}

Abken, Hinrich ^{[1
,2
]}

机构：

[1] Uniklin Koln, Zentrum Mol Med Koln, D-50937 Cologne, Germany

[2] Uniklin Koln, Innere Med Klin 1, D-50937 Cologne, Germany

[3] Max Delbruck Centrum Mol Med, D-13125 Berlin, Germany

[4] Paul Ehrlich Inst, D-63225 Langen, Germany

[5] Univ Manchester, Paterson Inst Canc Res, Dept Med Oncol, Manchester M20 4BX, Lancs, England

来源：

HUMAN GENE THERAPY | 2010年 / 21卷 / 09期

关键词：

SUICIDE-GENE; PHASE-I; IMMUNOTHERAPY; LYMPHOCYTES; LEUKEMIA; IMMUNORECEPTORS; SAFETY; TRIAL;

D O I：

10.1089/hum.2010.131

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1039 / 1042

页数：4

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