Synthesis of novel fluorophenylaryl/heteroaryl ether derivatives

被引：3

作者：

Das, Biplab K. ^{[1
]}

Shibata, Norio ^{[2
]}

Harada, Kazuyuki ^{[3
]}

Torub, Takeshi ^{[2
]}

机构：

[1] E W Univ, Dept Pharm, 43 Mohakhali C A, Dhaka 1212, Bangladesh

[2] Nagoya Inst Technol, Grad Sch Engn, Dept Appl Chem, Showa Ku, Nagoya, Aichi 4630031, Japan

[3] Toyama Med & Pharmaceut Univ, Fac Pharmaceut Sci, Toyama 9300194, Japan

来源：

ARKIVOC | 2007年

关键词：

synthesis; flurophenylaryl; /; heteroaryl; ether derivatives; phenolic coupling; hydrogenation;

D O I：

10.3998/ark.5550190.0008.g08

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

A detailed syntheses of some fluorophenylaryl / heteroaryl ether derivatives 1a, b-4a, b have been described which was accomplished by using a variety of convenient phenolic coupling methods and subsequent Pd-C catalyzed hydrogenation of the coupled intermediates. The compounds synthesized are structurally similar to a number of anti-inflammatory agents.

引用

页码：73 / 82

页数：10

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