Dynamic combinatorial libraries of metalloporphyrins: templated amplification of disulfide-linked oligomers

被引：84

作者：

Kieran, AL ^{[1
]}

Bond, AD ^{[1
]}

Belenguer, AM ^{[1
]}

Sanders, JKM ^{[1
]}

机构：

[1] Univ Cambridge, Cambridge Ctr Mol Recognit, Chem Lab, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 21期

关键词：

D O I：

10.1039/b310438a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Disulfide-linked cyclic porphyrin oligomers from dimer to tetramer can be selected and amplified virtually quantitatively from a dynamic combinatorial library using bis-thiol substituted zinc(II) porphyrin units with appropriate amine donor templates.

引用

页码：2674 / 2675

页数：2

共 14 条

[1] ENZYME MIMICS BASED ON CYCLIC PORPHYRIN OLIGOMERS - STRATEGY, DESIGN AND EXPLORATORY SYNTHESIS [J].

ANDERSON, HL ;

SANDERS, JKM .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1995, (18) :2223-2229

[2] TEMPLATE-DIRECTED SYNTHESIS OF LINEAR AND CYCLIC BUTADIYNE-LINKED PORPHYRIN OLIGOMERS UP TO A LINEAR OCTAMER [J].

ANDERSON, S ;

ANDERSON, HL ;

SANDERS, JKM .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1995, (18) :2247-2254

[3] Selection and amplification of a catalyst from a dynamic combinatorial library [J].

Brisig, B ;

Sanders, JKM ;

Otto, S .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (11) :1270-1273

[4] Chemical evolution: A model system that selects and amplifies a receptor for the tripeptide (D)Pro(L)Val(D)Val [J].

Hioki, H ;

Still, WC .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (04) :904-905

[5] EXCITON COUPLING IN PORPHYRIN DIMERS [J].

HUNTER, CA ;

SANDERS, JKM ;

STONE, AJ .

CHEMICAL PHYSICS, 1989, 133 (03) :395-404

[6] DABCO METALLOPORPHYRIN BINDING - TERNARY COMPLEXES, HOST GUEST CHEMISTRY, AND THE MEASUREMENT OF PI-PI-INTERACTIONS [J].

HUNTER, CA ;

MEAH, MN ;

SANDERS, JKM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (15) :5773-5780

[7] Synthesis, structure, and modeling of a cyclic rhodium(III) porphyrin dimer with an encapsulated 4,4′-bipyridine ligand [J].

Kim, HJ ;

Redman, JE ;

Nakash, M ;

Feeder, N ;

Teat, SJ ;

Sanders, JKM .

INORGANIC CHEMISTRY, 1999, 38 (22) :5178-+

[8] Dynamic covalent chemistry on self-templating peptides:: Formation of a disulfide-linked β-hairpin mimic [J].

Krishnan-Ghosh, Y ;

Balasubramanian, S .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (19) :2171-2173

[9] Chemistry - Dynamic combinatorial chemistry [J].

Lehn, JM ;

Eliseev, AV .

SCIENCE, 2001, 291 (5512) :2331-2332

[10] Dynamic combinatorial chemistry [J].

Otto, S ;

Furlan, RLE ;

Sanders, JKM .

DRUG DISCOVERY TODAY, 2002, 7 (02) :117-125

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