Practical reduction of carbonyl compounds with NaBH4 and silica gel in an aprotic solvent

被引:18
作者
Yakabe, S [1 ]
Hirano, M [1 ]
Morimoto, T [1 ]
机构
[1] Tokyo Univ Agr & Technol, Fac Technol, Dept Appl Chem, Tokyo 1848588, Japan
关键词
D O I
10.1080/00397919908085770
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Selective and high-yielding synthesis of alcohols can be easily achieved by the reduction of a variety of ketones and aldehydes with a combination of inexpensive and readily available laboratory reagents, NaBH4 and silica gel, in hexane under mild and neutral conditions.
引用
收藏
页码:295 / 302
页数:8
相关论文
共 28 条
[1]  
[Anonymous], 1993, ORGANIC CHEM USING C
[2]  
CIURDARU V, 1977, REV ROUM CHIM, V22, P1027
[3]  
Clark J.H., 1994, CATALYSIS ORGANIC RE
[4]  
CLARK JH, 1992, SUPPORTED REAGENTS P
[5]   SOME OBSERVATIONS ON BAEYER-VILLIGER OXIDATION OF ALICYCLIC KETONES WITH MAGNESIUM MONOPEROXYPHTHALTE IN APROTIC-SOLVENT IN THE PRESENCE OF BENTONITE CLAY [J].
HIRANO, M ;
UENO, Y ;
MORIMOTO, T .
SYNTHETIC COMMUNICATIONS, 1995, 25 (23) :3765-3775
[6]   A convenient deprotection of 1,3-dithiane derivatives with ferric nitrate under heterogeneous conditions [J].
Hirano, M ;
Ukawa, K ;
Yakabe, S ;
Morimoto, T .
SYNTHETIC COMMUNICATIONS, 1997, 27 (09) :1527-1533
[7]   Oxidation of various alcohols with in situ generated montmorillonite K10-supported ferric nitrate reagent in an aprotic solvent [J].
Hirano, M ;
Komiya, K ;
Morimoto, T .
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1995, 27 (06) :703-706
[8]   Manganese(III)-catalysed oxidation of sulphides with sodium chlorite in an aprotic solvent in the presence of alumina [J].
Hirano, M ;
Yakabe, S ;
Clark, JH ;
Kudo, H ;
Morimoto, T .
SYNTHETIC COMMUNICATIONS, 1996, 26 (10) :1875-1886
[9]   Regiospecific aromatic chlorination of alkyl phenyl ethers using sodium chlorite catalysed by manganese(III) acetylacetonate and moist alumina in dichloromethane [J].
Hirano, M ;
Yakabe, S ;
Monobe, H ;
Clark, JH ;
Morimoto, T .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1997, (20) :3081-3085
[10]   Dethioacetalization of dithiolanes with ferric nitrate and silica gel in hexane [J].
Hirano, M ;
Ukawa, K ;
Yakabe, S ;
Morimoto, T .
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1997, 29 (04) :480-484