A new cytotoxic cholestane bisdesmoside from Ornithogalum saundersiae bulbs

被引：12

作者：

Mimaki, Y ^{[1
]}

Kuroda, M ^{[1
]}

Kameyama, A ^{[1
]}

Sashida, Y ^{[1
]}

Hirano, T ^{[1
]}

Oka, K ^{[1
]}

Koike, K ^{[1
]}

Nikaido, T ^{[1
]}

机构：

[1] TOHO UNIV, SCH PHARMACEUT SCI, FUNABASHI, CHIBA 274, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 06期

关键词：

cholestane bisdesmoside; Ornithogalum saundersiae; cytotoxic activity; HL-60; cells; MOLT-4;

D O I：

10.1271/bbb.60.1049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Bioassay-guided fractionation of the MeOH extract of Ornithogalum saundersiae bulbs led to the isolation of a new cholestane bisdesmoside with potent cytotoxic activities toward leukemia HL-60 and MOLT-4 cells. The structure was deduced mainly from spectroscopic information.

引用

页码：1049 / 1050

页数：2

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