Modifying chromatin and concepts of cancer

被引：110

作者：

Jacobson, S ^{[1
]}

Pillus, L ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Biol 0347, La Jolla, CA 92093 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1999年 / 9卷 / 02期

关键词：

D O I：

10.1016/S0959-437X(99)80027-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A wave of biochemical and genetic progress has identified proteins that influence transcription by modifying chromatin. Many such factors are broadly conserved and, strikingly, occur in human diseases as partners in chromosomal translocations. Understanding the function of these factors will be key to defining mechanisms of transcriptional regulation and understanding cancers linked to aberrant chromatin modification.

引用

页码：175 / 184

页数：10

共 105 条

[41] Transcription factor-specific requirements for coactivators and their acetyltransferase functions [J].

Korzus, E ;

Torchia, J ;

Rose, DW ;

Xu, L ;

Kurokawa, R ;

McInerney, EM ;

Mullen, TM ;

Glass, CK ;

Rosenfeld, MG .

SCIENCE, 1998, 279 (5351) :703-707

[42]

Kuo MH, 1998, BIOESSAYS, V20, P615, DOI 10.1002/(SICI)1521-1878(199808)20:8<615::AID-BIES4>3.0.CO

[43]

2-H

[44] Acute mixed lineage, leukemia with an inv(8)(p11g13) resulting in fusion of the genes for MOZ and TIF2 [J].

Liang, J ;

Prouty, L ;

Williams, BJ ;

Dayton, MA ;

Blanchard, KL .

BLOOD, 1998, 92 (06) :2118-2122

[45] Binding and modulation of p53 by p300/CBP coactivators [J].

Lill, NL ;

Grossman, SR ;

Ginsberg, D ;

DeCaprio, J ;

Livingston, DM .

NATURE, 1997, 387 (6635) :823-827

[46] ADENOVIRAL E1A-ASSOCIATED PROTEIN P300 AS A FUNCTIONAL HOMOLOG OF THE TRANSCRIPTIONAL COACTIVATOR CBP [J].

LUNDBLAD, JR ;

KWOK, RPS ;

LAURANCE, ME ;

HARTER, ML ;

GOODMAN, RH .

NATURE, 1995, 374 (6517) :85-88

[47] ANALYSIS OF THE MURINE ALL-1 GENE REVEALS CONSERVED DOMAINS WITH HUMAN ALL-1 AND IDENTIFIES A MOTIF SHARED WITH DNA METHYLTRANSFERASES [J].

MA, Q ;

ALDER, H ;

NELSON, KK ;

CHATTERJEE, D ;

GU, Y ;

NAKAMURA, T ;

CANAANI, E ;

CROCE, CM ;

SIRACUSA, LD ;

BUCHBERG, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (13) :6350-6354

[48] Retinoblastoma protein represses transcription by recruiting a histone deacetylase [J].

Magnaghi-Jaulin, L ;

Groisman, R ;

Naguibneva, I ;

Robin, P ;

Lorain, S ;

Le Villain, JP ;

Troalen, F ;

Trouche, D ;

Harel-Bellan, A .

NATURE, 1998, 391 (6667) :601-605

[49] The acetyltransferase activity of CBP stimulates transcription [J].

Martínez-Balbás, MA ;

Bannister, AJ ;

Martin, K ;

Haus-Seuffert, P ;

Meisterernst, M ;

Kouzarides, T .

EMBO JOURNAL, 1998, 17 (10) :2886-2893

[50] Distinct steady-state nuclear receptor coregulator complexes exist in vivo [J].

McKenna, NJ ;

Nawaz, Z ;

Tsai, SY ;

Tsai, MJ ;

O'Malley, BW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (20) :11697-11702

← 1 2 3 4 5 6 7 8 9 10 →