Pathological and karyotypic abnormalities in advanced gastric carcinomas

被引：9

作者：

Espinoza, LA

Neto, JB

Casartelli, C

机构：

[1] Univ Fed Sao Paulo, Fac Med Ribeirao Preto, Dept Genet, Ribeirao Preto, Brazil

[2] Univ Fed Sao Paulo, Fac Med Ribeirao Preto, Dept Pathol, Ribeirao Preto, Brazil

来源：

CANCER GENETICS AND CYTOGENETICS | 1999年 / 109卷 / 01期

基金：

巴西圣保罗研究基金会;

关键词：

D O I：

10.1016/S0165-4608(98)00149-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Twenty samples of stomach cancers were analyzed by conventional cytogenetic and histopathological techniques. Nineteen tumors were diagnosed as adenocarcinomas and one as an adenosquamous carcinoma, Multiple and complex chromosomal abnormalities were found in the cases evaluated cytogenetically. This heterogeneity of chromosomal changes appears to indicate a certain correlation with tumor progression. Histological analysis showed a distinctive growth pattern of gastric cancer samples and a potential for invasiveness and recurrence for all tumors as well as a poor prognosis. (C) Elsevier Science Inc., 1999. All rights reserved.

引用

收藏

页码：45 / 50

页数：6

相关论文

共 35 条

[21] CYTOGENETIC STUDY OF 11 GASTRIC ADENOCARCINOMAS [J].

PANANI, AD ;

FERTI, A ;

MALLIAROS, S ;

RAPTIS, S .

CANCER GENETICS AND CYTOGENETICS, 1995, 81 (02) :169-172

[22] INTERSTITIAL DELETION OF THE SHORT ARM OF CHROMOSOME-3 AS A PRIMARY CHROMOSOME ABNORMALITY IN CARCINOMAS OF THE BREAST [J].

PANDIS, N ;

JIN, YS ;

LIMON, J ;

BARDI, G ;

IDVALL, I ;

MANDAHL, N ;

MITELMAN, F ;

HEIM, S .

GENES CHROMOSOMES & CANCER, 1993, 6 (03) :151-155

[23] FAMILIAL RENAL-CELL CARCINOMA WITH A 3-11 CHROMOSOME-TRANSLOCATION LIMITED TO TUMOR-CELLS [J].

PATHAK, S ;

STRONG, LC ;

FERRELL, RE ;

TRINDADE, A .

SCIENCE, 1982, 217 (4563) :939-941

[24] CYTOGENETICS OF GASTRIC AND ESOPHAGEAL ADENOCARCINOMAS - 3Q DELETION AS A POSSIBLE PRIMARY CHROMOSOMAL CHANGE [J].

RAO, PH ;

MATHEW, S ;

KELSEN, DP ;

CHAGANTI, RSK .

CANCER GENETICS AND CYTOGENETICS, 1995, 81 (02) :139-143

[25]

RODRIGUEZ E, 1990, CANCER RES, V50, P6410

[26]

SAINSBURY JRC, 1985, LANCET, V1, P364

[27] CHROMOSOMAL-ABNORMALITIES AND RELATED EVENTS IN PROSTATE-CANCER [J].

SANDBERG, AA .

HUMAN PATHOLOGY, 1992, 23 (04) :368-380

[28] CYTOGENETIC FINDINGS IN 11 GASTRIC CARCINOMAS [J].

SERUCA, R ;

CASTEDO, S ;

CORREIA, C ;

GOMES, P ;

CARNEIRO, F ;

SOARES, P ;

DEJONG, B ;

SOBRINHOSIMOES, M .

CANCER GENETICS AND CYTOGENETICS, 1993, 68 (01) :42-48

[29] THE MOLECULAR-BIOLOGY OF ESOPHAGEAL AND GASTRIC-CANCER AND THEIR PRECURSORS - ONCOGENES, TUMOR-SUPPRESSOR GENES, AND GROWTH-FACTORS [J].

STEMMERMANN, G ;

HEFFELFINGER, SC ;

NOFFSINGER, A ;

HUI, YZ ;

MILLER, MA ;

FENOGLIOPREISER, CM .

HUMAN PATHOLOGY, 1994, 25 (10) :968-981

[30] CYTOGENETIC STUDIES OF GASTRIC ADENOCARCINOMA [J].

TZENG, CC ;

MENG, CL ;

JIN, L ;

HSIEH, HF .

CANCER GENETICS AND CYTOGENETICS, 1991, 55 (01) :67-71

← 1 2 3 4 →