Rapid and reliable diagnostic algorithm for detection of Clostridium difficile

被引：115

作者：

Fenner, Lukas ^{[1
]}

Widmer, Andreas F. ^{[2
,3
]}

Goy, Gisela ^{[1
]}

Rudin, Sonja ^{[1
]}

Frei, Reno ^{[1
]}

机构：

[1] Univ Basel Hosp, Microbiol Lab, CH-4031 Basel, Switzerland

[2] Univ Basel Hosp, Div Infect Dis, CH-4031 Basel, Switzerland

[3] Univ Basel Hosp, Hosp Epidemiol, CH-4031 Basel, Switzerland

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 01期

关键词：

D O I：

10.1128/JCM.01503-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We evaluated a two-step algorithm for detection of Clostridium difficile in 1,468 stool specimens. First, specimens were screened by an immunoassay for C. difficile glutamate dehydrogenase antigen (C.DIFF CHEK60). Second, screen-positive specimens underwent toxin testing by a rapid toxin A/B assay (TOX A/B QUIK CHEK); toxin-negative specimens were subjected to stool culture. This algorithm allowed final results for 92% of specimens with a turnaround time of 4 h.

引用

页码：328 / 330

页数：3

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