Naive application of permutation testing leads to inflated type I error rates

被引：46

作者：

Churchill, G. A. ^{[2
]}

Doerge, R. W. ^{[1
]}

机构：

[1] Purdue Univ, W Lafayette, IN 47907 USA

[2] Jackson Lab, Bar Harbor, ME 04609 USA

来源：

GENETICS | 2008年 / 178卷 / 01期

关键词：

D O I：

10.1534/genetics.107.074609

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Failure to account for family structure within populations or in complex mating designs via uninformed applications of permutation testing will lead to inflated type I error rates. Careful consideration of the design factors is essential since sonic situations allow several valid permutation strategies, and the choice that maximizes statistical power will not always be intuitive.

引用

页码：609 / 610

页数：2

共 5 条

[1] Permutation tests for multi-factorial analysis of variance [J].