Study of the Lewis acid-promoted imines derived from addition of silylenol ethers to glyceraldehyde

被引：22

作者：

Badorrey, R ^{[1
]}

Cativiela, C ^{[1
]}

Díaz-de-Villegas, MD ^{[1
]}

Gálvez, JA ^{[1
]}

机构：

[1] Univ Zaragoza, CSIC,Inst Ciencia Mat Aragon, Fac Ciencias, Dept Quim Organ, E-50009 Zaragoza, Spain

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 51期

关键词：

asymmetric synthesis; imines; Mannich reaction;

D O I：

10.1016/j.tetlet.2003.10.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral N-benzylimines derived form D-glyceraldehyde undergo Lewis acid-promoted asymmetric Mannich reactions with O-methyl-O-trimethylsilyl dimethylketeneacetal to give beta-amino acid esters in good yields and with excellent diastereoselectivities. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：9189 / 9192

页数：4

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