First bodipy-DOTA derivatives as probes for bimodal imaging

被引:58
作者
Bernhard, Claire [1 ]
Goze, Christine [1 ]
Rousselin, Yoann [1 ]
Denat, Franck [1 ]
机构
[1] Univ Bourgogne, CNRS, UMR 5260, Inst Chim Mol, F-21078 Dijon, France
关键词
MRI CONTRAST AGENTS; SPECTRAL PROPERTIES; COMPLEXES; DESIGN; DYES;
D O I
10.1039/c0cc02749a
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
The synthesis and the photophysical studies of the first bodipy-DOTA and its In(III), Ga(III) and Cu(II) complexes are reported. The introduction of an isothiocyanate handle generates a new bimodal imaging agent capable of both optical and nuclear imaging.
引用
收藏
页码:8267 / 8269
页数:3
相关论文
共 33 条
[1]
In vivo imaging of gene and cell therapies [J].
Allport, JR ;
Weissleder, R .
EXPERIMENTAL HEMATOLOGY, 2001, 29 (11) :1237-1246
[2]
Lanthanide(III) complexes of DOTA-glycoconjugates:: A potential new class of lectin-mediated medical imaging agents [J].
André, JP ;
Geraldes, CFGC ;
Martins, JA ;
Merbach, AE ;
Prata, MIM ;
Santos, AC ;
de Lima, JJP ;
Tóth, É .
CHEMISTRY-A EUROPEAN JOURNAL, 2004, 10 (22) :5804-5816
[3]
Intramolecular charge transfer in pyrromethene laser dyes:: Photophysical behaviour of PM650 [J].
Arbeloa, FL ;
Prieto, JB ;
Martínez, VM ;
López, TA ;
Arbeloa, IL .
CHEMPHYSCHEM, 2004, 5 (11) :1762-1771
[4]
Design, synthesis and in vitro characterization of Glucagon-Like Peptide-1 derivatives for pancreatic beta cell imaging by SPECT [J].
Azad, Babak Behnam ;
Rota, Vanessa A. ;
Breadner, Daniel ;
Dhanvantari, Savita ;
Luyt, Leonard G. .
BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 18 (03) :1265-1272
[5]
Convenient synthesis of water-soluble nitrilotriacetic acid (NTA) BODIPY dyes [J].
Brellier, Marie ;
Duportail, Guy ;
Baati, Rachid .
TETRAHEDRON LETTERS, 2010, 51 (09) :1269-1272
[6]
Gadolinium(III) chelates as MRI contrast agents: Structure, dynamics, and applications [J].
Caravan, P ;
Ellison, JJ ;
McMurry, TJ ;
Lauffer, RB .
CHEMICAL REVIEWS, 1999, 99 (09) :2293-2352
[7]
Strategies for increasing the sensitivity of gadolinium based MRI contrast agents [J].
Caravan, Peter .
CHEMICAL SOCIETY REVIEWS, 2006, 35 (06) :512-523
[8]
Targeted alpha-radionuclide therapy of functionally critically located gliomas with 213Bi-DOTA-[Thi8,Met(O2)11]-substance P: a pilot trial [J].
Cordier, D. ;
Forrer, F. ;
Bruchertseifer, F. ;
Morgenstern, A. ;
Apostolidis, C. ;
Good, S. ;
Mueller-Brand, J. ;
Maecke, H. ;
Reubi, J. C. ;
Merlo, A. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2010, 37 (07) :1335-1344
[9]
Signal ratio amplification via modulation of resonance energy transfer: Proof of principle in an emission ratiometric Hg(II) sensor [J].
Coskun, Ali ;
Akkaya, Engin U. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (45) :14474-14475
[10]
Synthesis, spectral properties and photostability of novel boron-dipyrromethene dyes [J].
Cui, Aijun ;
Peng, Xiaojun ;
Fan, Jiangli ;
Chen, Xiuying ;
Wu, Yunkou ;
Guo, Binchen .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2007, 186 (01) :85-92