Effects of hormone replacement therapy on the endometrium and lipid parameters: A review of randomized clinical trials, 1985 to 1995

被引：57

作者：

Pickar, JH

Thorneycroft, I

Whitehead, M

机构：

[1] Wyeth Ayerst Res, Philadelphia, PA 19101 USA

[2] Univ S Alabama, Dept Obstet & Gynecol, Mobile, AL 36688 USA

[3] Kings Coll Hosp London, Menopause Clin, London, England

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1998年 / 178卷 / 05期

关键词：

hormone replacement therapy; estrogen; progestin; endometrial hyperplasia; lipoproteins; review article;

D O I：

10.1016/S0002-9378(98)70553-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The association between unopposed estrogen replacement therapy and endometrial hyperplasia and endometrial cancer in nonhysterectomized postmenopausal women is well known, and studies have suggested that the addition of progestin to the regimen reduces the risk of hyperplasia and cancer. The effect of estrogen plus progestin hormone replacement therapy on the lipid profile has also been extensively studied. To determine the extent of the effects of hormone replacement therapy on the endometrium and lipid parameters and to provide an overview of these studies, we reviewed 10 years of English language publications.

引用

页码：1087 / 1099

页数：13

共 57 条

[21] LONG-TERM EFFECTS OF PERCUTANEOUS ESTROGENS AND ORAL PROGESTERONE ON SERUM-LIPOPROTEINS IN POSTMENOPAUSAL WOMEN [J].

JENSEN, J ;

RIIS, BJ ;

STROM, V ;

NILAS, L ;

CHRISTIANSEN, C .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1987, 156 (01) :66-71

[22] Effects of hormone replacement therapy on endometrial histology in postmenopausal women - The Postmenopausal Estrogen Progestin Interventions (PEPI) trial [J].

Judd, HL ;

Wasilauskas, C ;

Johnson, S ;

Merino, M ;

BarrettConnor, E ;

Trabal, J ;

Miller, VT ;

Barnabei, V ;

Levin, G ;

Bush, T ;

Foster, D ;

Zacur, H ;

Woodruff, JD ;

Stefanick, M ;

Akana, A ;

Heinrichs, WL ;

OHanlan, K ;

Buyalos, RP ;

Greendale, G ;

Lozano, K ;

CarrionPetersen, L ;

Cavero, C ;

Langer, R ;

Schrott, HG ;

Benda, JA ;

deProsse, C ;

Fedderson, D ;

Johnson, SR ;

Ahmad, MM ;

Brown, HP ;

Schenken, RS ;

RodriguezSifuentes, M ;

Valente, PT ;

Espeland, M ;

Lane, K ;

Legault, C ;

MebaneSims, IL ;

Kelaghan, J ;

McGowan, J ;

Fradkin, J ;

Sherman, S ;

Scully, R .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (05) :370-375

[23]

KABLE WT, 1990, J REPROD MED, V35, P512

[24] EFFECTS OF HORMONE REPLACEMENT THERAPY ON LIPOPROTEIN(A) AND LIPIDS IN POSTMENOPAUSAL WOMEN [J].

KIM, CJ ;

JANG, HC ;

CHO, DH ;

MIN, YK .

ARTERIOSCLEROSIS AND THROMBOSIS, 1994, 14 (02) :275-281

[25] ENDOMETRIAL EFFECTS DURING HORMONE REPLACEMENT THERAPY WITH A SEQUENTIAL ESTRADIOL VALERATE CYPROTERONE-ACETATE PREPARATION [J].

KONINCKX, PR ;

LAUWERYNS, JM ;

CORNILLIE, FJ .

MATURITAS, 1993, 16 (02) :97-110

[26]

KURMAN RJ, 1985, CANCER, V56, P403, DOI 10.1002/1097-0142(19850715)56:2<403::AID-CNCR2820560233>3.0.CO

[27]

2-X

[28] EFFECTS OF CYPROTERONE-ACETATE (CPA) ON SERUM-LIPOPROTEINS WHEN ADMINISTERED ALONE AND IN COMBINATION WITH ETHINYL ESTRADIOL (EE) [J].

LINDBERG, UB ;

CRONA, N ;

ENK, L ;

SAMSIOE, G ;

SILFVERSTOLPE, G .

HORMONE AND METABOLIC RESEARCH, 1987, 19 (05) :222-225

[29] LP(A) LIPOPROTEIN - RELATIONSHIP TO CARDIOVASCULAR-DISEASE RISK-FACTORS, EXERCISE, AND ESTROGEN [J].

LOBO, RA ;

NOTELOVITZ, M ;

BERNSTEIN, L ;

KHAN, FY ;

ROSS, RK ;

PAUL, WL .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 166 (04) :1182-1190

[30]

LOBO RA, 1994, OBSTET GYNECOL, V84, P987

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