Genetics of Atrial Fibrillation Implications for Future Research Directions and Personalized Medicine

被引:57
作者
Lubitz, Steven A. [2 ,3 ]
Ozcan, Cevher [1 ]
Magnani, Jared W. [10 ]
Kaeaeb, Stefan [4 ]
Benjamin, Emelia J. [5 ,6 ,7 ,8 ,9 ]
Ellinor, Patrick T. [1 ,2 ]
机构
[1] Massachusetts Gen Hosp, Cardiac Arrhythmia Serv, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Cardiovasc Res Ctr, Boston, MA 02114 USA
[3] Brigham & Womens Hosp, Div Prevent Med, Boston, MA 02115 USA
[4] Univ Munich, Dept Med 1, Univ Hosp Grosshadern, Munich, Germany
[5] Boston Univ, Framingham, MA USA
[6] NHLBI, Framingham Heart Study, Framingham, MA USA
[7] Boston Univ, Sch Med, Dept Med, Boston, MA 02118 USA
[8] Boston Univ, Sch Med, Dept Prevent Med, Boston, MA 02118 USA
[9] Boston Univ, Sch Med, Whitaker Cardiovasc Inst, Boston, MA 02118 USA
[10] Boston Univ, Sch Med, Cardiol Sect, Boston, MA 02118 USA
关键词
atrial flutter; atrium; electrophysiology; epidemiology; fibrillation; genetics; ion channels; risk factors; OF-FUNCTION MUTATION; CONGESTIVE-HEART-FAILURE; SHORT QT SYNDROME; DILATED CARDIOMYOPATHY; FAMILIAL AGGREGATION; COMMON VARIANTS; SODIUM-CHANNEL; SOMATIC MUTATIONS; KCNQ1; MUTATION; PR INTERVAL;
D O I
10.1161/CIRCEP.110.942441
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:291 / 299
页数:9
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