Melatonin facilitates short-term memory

被引：64

作者：

Argyriou, A ^{[1
]}

Prast, H ^{[1
]}

Philippu, A ^{[1
]}

机构：

[1] Univ Innsbruck, Dept Pharmacol & Toxicol, A-6020 Innsbruck, Austria

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1998年 / 349卷 / 2-3期

关键词：

memory; short-term; melatonin; luzindole; (rat);

D O I：

10.1016/S0014-2999(98)00300-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The olfactory social memory test, based on the recognition of a juvenile rat by a male adult rat, was used to investigate whether melatonin influences memory, Intracerebroventricular (i.c.v.) injection of 1.1 nmol melatonin shortened recognition time, while the melatonin ML(1) receptor antagonist luzindole (1 nmol) exerted the opposite effect. The facilitating influence of melatonin was abolished in the presence of 0.5 nmol luzindole. The findings suggest that endogenous melatonin facilitates short-term memory. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：159 / 162

页数：4