Functional organization of spatial and nonspatial working memory processing within the human lateral frontal cortex

被引:281
作者
Owen, AM
Stern, CE
Look, RB
Tracey, I
Rosen, BR
Petrides, M
机构
[1] MRC, Appl Psychol Unit, Cambridge CB2 2EF, England
[2] Massachusetts Gen Hosp, Nucl Magnet Resonance Ctr, Charlestown, MA 02129 USA
[3] McGill Univ, Montreal Neurol Inst, Cognit Neurosci Lab, Montreal, PQ H3A 2B4, Canada
关键词
D O I
10.1073/pnas.95.13.7721
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The present study used functional magnetic resonance imaging to demonstrate that performance of visual spatial and visual nonspatial working memory tasks involve the same regions of the lateral prefrontal cortex when all factors unrelated to the type of stimulus material are appropriately controlled. These results provide evidence that spatial and nonspatial working memory may not be mediated, respectively, by mid-dorsolateral and mid-ventrolateral regions of the frontal lobe, as widely assumed, and support the alternative notion that specific regions of the lateral prefrontal cortex make identical executive functional contributions to both spatial and nonspatial working memory.
引用
收藏
页码:7721 / 7726
页数:6
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