Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals

被引：125

作者：

Byrnes, Edmond J., III ^{[1
]}

Bartlett, Karen H. ^{[3
]}

Perfect, John R. ^{[2
]}

Heitman, Joseph ^{[1
,2
]}

机构：

[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA

[3] Univ British Columbia, Sch Environm Hlth, Vancouver, BC V5Z 1M9, Canada

来源：

MICROBES AND INFECTION | 2011年 / 13卷 / 11期

关键词：

Fungal infections; Cryptococcosis; Emerging outbreak; Pulmonary disease; Meningitis; NEOFORMANS VAR. GATTII; VANCOUVER-ISLAND OUTBREAK; MOLECULAR TYPE-VGII; PAPUA-NEW-GUINEA; BRITISH-COLUMBIA; MATING-TYPE; PACIFIC-NORTHWEST; UNITED-STATES; ANTIFUNGAL SUSCEPTIBILITIES; ENVIRONMENTAL ISOLATION;

D O I：

10.1016/j.micinf.2011.05.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

071005 [微生物学]; 100108 [医学免疫学];

摘要：

Infectious fungi are among a broad group of microbial pathogens that has and continues to emerge concomitantly due to the global AIDS pandemic as well as an overall increase of patients with compromised immune systems. In addition, many pathogens have been emerging and re-emerging, causing disease in both individuals who have an identifiable immune defect and those who do not. The fungal pathogen Cryptococcus gattii can infect individuals with and without an identifiable immune defect, with a broad geographic range including both endemic areas and emerging outbreak regions. Infections in patients and animals can be severe and often fatal if untreated. We review the molecular epidemiology, population structure, clinical manifestations, and ecological niche of this emerging pathogen. (C) 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：895 / 907

页数：13

共 127 条

[1]

Feline pyothorax: a retrospective study of 27 cases in Australia [J].

Barrs, VR ;

Allan, GS ;

Beatty, JA ;

Malik, R .

JOURNAL OF FELINE MEDICINE AND SURGERY, 2005, 7 (04) :211-222

[2]

The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest [J].

Bartlett K.H. ;

Kidd S.E. ;

Kronstad J.W. .

Current Infectious Disease Reports, 2008, 10 (1) :58-65

[3]

Beatty J A, 2000, J Feline Med Surg, V2, P29, DOI 10.1053/jfms.2000.0061

[4]

Successful treatment of cryptococcal pneumonia in a pony mare [J].

Begg, LM ;

Hughes, KJ ;

Kessell, A ;

Krockenberger, MB ;

Wigney, DI ;

Malik, R .

AUSTRALIAN VETERINARY JOURNAL, 2004, 82 (11) :686-692

[5]

Bat White-Nose Syndrome: An Emerging Fungal Pathogen? [J].

Blehert, David S. ;

Hicks, Alan C. ;

Behr, Melissa ;

Meteyer, Carol U. ;

Berlowski-Zier, Brenda M. ;

Buckles, Elizabeth L. ;

Coleman, Jeremy T. H. ;

Darling, Scott R. ;

Gargas, Andrea ;

Niver, Robyn ;

Okoniewski, Joseph C. ;

Rudd, Robert J. ;

Stone, Ward B. .

SCIENCE, 2009, 323 (5911) :227-227

[6]

Cryptococcus neoformans var. gattii meningitis in an HIV-positive patient:: first observation in the United Kingdom [J].

Bodasing, N ;

Seaton, RA ;

Shankland, GS ;

Kennedy, D .

JOURNAL OF INFECTION, 2004, 49 (03) :253-255

[7]

Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans [J].

Boekhout, T ;

Theelen, B ;

Diaz, M ;

Fell, JW ;

Hop, WCJ ;

Abeln, ECA ;

Dromer, F ;

Meyer, W .

MICROBIOLOGY-UK, 2001, 147 :891-907

[8]

Six monophyletic lineages identified within Cryptococcus neoformans and Cryptococcus gattii by multi-locus sequence typing [J].

Bovers, M. ;

Hagen, F. ;

Kuramae, E. E. ;

Boekhout, T. .

FUNGAL GENETICS AND BIOLOGY, 2008, 45 (04) :400-421

[9]

Promiscuous mitochondria in Cryptococcus gattii [J].

Bovers, Marjan ;

Hagen, Ferry ;

Kuramae, Eiko E. ;

Boekhout, Teun .

FEMS YEAST RESEARCH, 2009, 9 (03) :489-503

[10]

Iridovirus and Microsporidian Linked to Honey Bee Colony Decline [J].

Bromenshenk, Jerry J. ;

Henderson, Colin B. ;

Wick, Charles H. ;

Stanford, Michael F. ;

Zulich, Alan W. ;

Jabbour, Rabih E. ;

Deshpande, Samir V. ;

McCubbin, Patrick E. ;

Seccomb, Robert A. ;

Welch, Phillip M. ;

Williams, Trevor ;

Firth, David R. ;

Skowronski, Evan ;

Lehmann, Margaret M. ;

Bilimoria, Shan L. ;

Gress, Joanna ;

Wanner, Kevin W. ;

Cramer, Robert A., Jr. .

PLOS ONE, 2010, 5 (10)

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